Publications


Amortized Adaptive Importance Sampling for Variational Autoencoder

Gwangwoo Kim and Hyonho Chun

Under review (2024)


Factors associated with gastric and duodenal neuroendocrine tumors: A multicenter case-control study 

Kwangwoo Nam, Su Youn Nam, Jun Chul Park, Young Sin Cho, Hyuk Soon Choi, Kyoungwon Jung, Seon-Young Park, Joon Hyun Cho, Hyonho Chun

Digestive and Liver Disease (2024)


Similarity-assisted Variational Autoencoder for Nonlinear Dimension Reduction with Application to Single-cell RNA Sequencing Data

Gwangwoo Kim and Hyonho Chun

BMC Bioinformatics (2023)


A prediction model for healthcare time-series data with a mixture of deep mixed effect models using Gaussian processes

Jaehyoung Hong and Hyonho Chun

Biomedical Signal Processing and Control (2023)


Sex-specific effects of fruit, vegetable, and red meat intake on the risk of gastric and esophageal cancer in a large cohort 

SuYoun Nam, Junwoo Jo, SeongWoo Jeon, Hyonho Chun

Digestive and Liver Disease (2023)


Deep nonnegative matrix factorization using a variational autoencoder with application to single-cell RNA sequencing data
D. Jee, Y. Kong, and H. Chun
IEEE/ACM Transactions on Computational Biology and Bioinformatics (2022)


scAVENGERS: a genotype-based deconvolution of individuals in multiplexed single-cell ATAC-seq data without reference genotypes 

Seungbeom Han, Kyukwang Kim, Seongwan Park, Andrew J Lee, Hyonho Chun, Inkyung Jung

NAR Genomics and Bioinformatics (2022) 


Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery 

Yeon-Suk Yang, Jung-Min Kim, Jun Xie, Sachin Chaugule, Chujiao Lin, Hong Ma, Edward Hsiao, Jaehyoung Hong, Hyonho Chun, Eileen M Shore, Frederick S Kaplan, Guangping Gao, Jae-Hyuck Shim

Nature communications (2022)


Biphasic regulation of osteoblast development via the ERK MAPK–mTOR pathway 

Jung-Min Kim, Yeon-Suk Yang, Jaehyoung Hong, Sachin Chaugule, Hyonho Chun, Marjolein CH van Der Meulen, Ren Xu, Matthew B Greenblatt, Jae-hyuck Shim 

Elife (2022)


FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity 

Hilde Herrema, Dongxian Guan, Jae Won Choi, Xudong Feng, Mario Andres Salazar Hernandez, Farhana Faruk, Thomas Auen, Eliza Boudett, Rongya Tao, Hyonho Chun, Umut Ozcan

Cell metabolism (2022)


Clinical impact of clonal hematopoiesis on severe COVID-19 patients without canonical risk factors 

Chang Kyung Kang, Baekgyu Choi, Sugyeong Kim, Choong Hyun Sun, Soon Ho Yoon, Kyukwang Kim, Euijin Chang, Jongtak Jung, Pyoeng Gyun Choe, Wan Beom Park, Eu Suk Kim, Hong Bin Kim, Nam Joong Kim, Myoung-don Oh, Hogune Im, Joohae Kim, Yong Hoon Lee, Jaehee Lee, Hyonho Chun, Youngil Koh, Ji Yeon Lee, Joon Ho Moon, Kyoung-Ho Song, Inkyung Jung

Haematologica (2022)


Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes
JM Kim, YS Yang, J Xie, O Lee, JH Kim, J Hong, B Boldyreff, O Filhol, H Chun, MB Greeblatt, G Gao, JH Shim
Cell Death & Differentiation (2022)


Impaired ERK MAPK activation in mature osteoblasts enhances bone formation via the mTOR pathway
JM Kim, YS Yang, J Hong, S Chaugule, H Chun, MCH van der Meulen, R Xu, MB Greenblatt, JH Shim
bioRxiv (2022)


A zero-inflated non-negative matrix factorization for the deconvolution of mixed signals of biological data
Y Kong, A Kozik, CH Nakatsu, YL Jones-Hall, and H Chun
International Journal of Biostatistics, (2021)


Proteomic and metabolomic profiling reveals the involvement of apoptosis in meat quality characteristics of ovine M. longissimus from different callipyge genotypes
Danyi Ma, Qianqian Yu, Vicki E Hendrick, Bruce R Cooper, Tiago Sobreira, Ji-Hwan Oh, Hyonho Chun, Yuan H Brad Kim
Meat Science (2020)


A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation
Jung-Min Kim, Yeon-Suk Yang, Kwang Hwan Park, Xianpeng Ge, Ren Xu, Na Li, Minkyung Song, Hyonho Chun, Seoyeon Bok, Julia F Charles, Odile Filhol-Cochet, Brigitte Boldyreff, Teresa Dinter, B Yu Paul, Ning Kon, Wei Gu, Takeshi Takarada, Matthew B Greenblatt, Jae-Hyuck Shim
Nature communications 11, 1 (2020)


FIREVAT: finding reliable variants without artifacts in human cancer samples using etiologically relevant mutational signatures
Hyunbin Kim, Andy Jinseok Lee, Jongkeun Lee, Hyonho Chun, Young Seok Ju, Dongwan Hong
Genome medicine 11, 1 (2019)


Comparison of the fecal, cecal, and mucus microbiome in male and female mice after TNBS-induced colitis
Ariangela J Kozik, Cindy H Nakatsu, Hyonho Chun, Yava L Jones-Hall
PloS one 14, 11 (2019)


Learning dispatching rules using random forest in flexible job shop scheduling problems
Sungbum Jun, Seokcheon Lee, Hyonho Chun
International Journal of Production Research 57, 10 (2019)


IL1R1 is required for celastrol’s leptin-sensitization and antiobesity effects
Xudong Feng, Dongxian Guan, Thomas Auen, Jae Won Choi, Mario Andres Salazar Hernandez, Jaemin Lee, Hyonho Chun, Farhana Faruk, Esther Kaplun, Zachary Herbert, Kyle D Copps, Umut Ozcan
Nature medicine 25, 4 (2019)


A Nonnegative Robust Linear Model for Deconvolution of Proportions
Hyonho Chun, Hyuna Yang
Contemporary Biostatistics with Biopharmaceutical Applications (2019)


Spatial autocorrelation in soil compaction and its impact on earthwork acceptance testing
Jiannan Cai, Qingyi Gao, Hyonho Chun, Hubo Cai, Tommy Nantung
Transportation Research Record 2673, 1 (2019)


Kernel partial correlation: a novel approach to capturing conditional independence in graphical models for noisy data
Jihwan Oh, Faye Zheng, RW Doerge, Hyonho Chun
Journal of Applied Statistics 45, 14 (2018)


Mutalisk: a web-based somatic MUTation AnaLyIS toolKit for genomic, transcriptional and epigenomic signatures
Jongkeun Lee, Andy Jinseok Lee, June-Koo Lee, Jongkeun Park, Youngoh Kwon, Seongyeol Park, Hyonho Chun, Young Seok Ju, Dongwan Hong
Nucleic acids research 46, W1 (2018)


Robust precision matrix estimation via weighted median regression with regularization
Hyonho Chun, Myung Hee Lee, Sung‐Ho Kim, Jihwan Oh
Canadian Journal of Statistics 46, 2 (2018)


Optimal Sampling Strategy for Acceptance Decision in Highway Construction: a Cost–Benefit Analysis Approach
Jiannan Cai, Shuai Li, Qingyi Gao, Hyonho Chun, Tommy Nantung, Hubo Cai
Transportation Research Board 97th Annual MeetingTransportation Research Board (2018)


Age, sex, and TNF associated differences in the gut microbiota of mice and their impact on acute TNBS colitis
Ariangela J Kozik, Cindy H Nakatsu, Hyonho Chun, Yava L Jones-Hall
Experimental and molecular pathology 103, 3 (2017)


Involvement of Apoptosis in Meat Quality Attributes Using the Callipyge Lamb Model: I. the Omics Approach 

Danyi Ma, Moriah Penick, Bruce R Cooper, J-H Oh, Hyonho Chun, Jolena N Waddell, Chris A Bidwell, YH Brad Kim 

63rd International Congress of Meat Science and Technology (2017)


Metabolomics profiling to determine the effect of postmortem aging on color and lipid oxidative stabilities of different bovine muscles
Danyi Ma, Yuan H Brad Kim, Bruce Cooper, Ji-Hwan Oh, Hyonho Chun, Ju-Hui Choe, Jon P Schoonmaker, Kolapo Ajuwon, Byungrok Min
Journal of agricultural and food chemistry 65, 31 (2017)


Using pre-assessment and in-class questions to change student understanding of molecular movements
J Shi, Jennifer K Knight, Hyonho Chun, Nancy A Guild, Jennifer M Martin
Journal of microbiology & biology education 18, 1 (2017)


Graphical models via joint quantile regression with component selection
Hyonho Chun, Myung Hee Lee, James C Fleet, Ji Hwan Oh
Journal of Multivariate Analysis, 152 (2016)


Gene regulation network inference with joint sparse Gaussian graphical models
Hyonho Chun, Xianghua Zhang, Hongyu Zhao
Journal of Computational and Graphical Statistics 24, 4 (2015)


Effective simultaneous confidence bands for repeated measurements in linear mixed-effect models
Jungwon Mun, Hyonho Chun
Journal of Statistical Computation and Simulation 84, 8 (2014)


On an additive semigraphoid model for statistical networks with application to pathway analysis
Bing Li, Hyonho Chun, Hongyu Zhao
Journal of the American Statistical Association 109, 507 (2014)


Joint conditional Gaussian graphical models with multiple sources of genomic data
Hyonho Chun, Min Chen, Bing Li, Hongyu Zhao
Frontiers in genetics 4, (2013)


Sparse estimation of conditional graphical models with application to gene networks
Bing Li, Hyonho Chun, Hongyu Zhao
Journal of the American Statistical Association 107, 497 (2012)


Spls: sparse partial least squares (SPLS) regression and classification
Dongjun Chung, Hyonho Chun, Sunduz Keles
R package, version 2, (2012)


Identification of association between disease and multiple markers via sparse partial least‐squares regression
Hyonho Chun, David H Ballard, Judy Cho, Hongyu Zhao
Genetic epidemiology 35, 6 (2011)


Reverse Engineering of Gene Regulation Networks with an Application to the DREAM4 in silico Network Challenge
Hyonho Chun, Jia Kang, Xianghua Zhang, Minghua Deng, Haisu Ma, Hongyu Zhao
Handbook of Statistical Bioinformatics, (2011)


Visualizing abnormal climate changes in Central America from 1995 to 2000
Sang-Hoon Cho, Hyonho Chun
Computational Statistics 25, 4 (2010)


Simultaneous dimension reduction and variable selection with sparse partial least squares

H Chun, S Keles

 Journal of Royal Statistical Society B 72 (1), 3-25 (2010)


Sparse partial least squares regression for simultaneous dimension reduction and variable selection
Hyonho Chun, Sündüz Keleş
Journal of the Royal Statistical Society B (Statistical Methodology) 72, 1 (2010)


Genome-wide association studies using single-nucleotide polymorphisms versus haplotypes: an empirical comparison with data from the North American Rheumatoid Arthritis Consortium
Heejung Shim, Hyonho Chun, Corinne D Engelman, Bret A Payseur
BMC proceedings 3, 1 (2009)


Expression quantitative trait loci mapping with multivariate sparse partial least squares regression
Hyonho Chun, Sündüz Keleş
Genetics 182, 1 (2009)


Comments on: Augmenting the bootstrap to analyze high dimensional genomic data
Sündüz Keleş, Hyonho Chun
Test 17, 1 (2008)


CMARRT: a tool for the analysis of ChIP-chip data from tiling arrays by incorporating the correlation structure
Pei Fen Kuan, Hyonho Chun, Sündüz Keleş
Biocomputing (2008)